Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation

The MRE11–RAD50–NBS1 (MRN) complex is well known for participating in DNA damage response pathways in all phases of cell cycle. Here, we show that MRN constitutes a mitosis-specific complex, named mMRN, with a protein, MMAP. MMAP directly interacts with MRE11 and is required for optimal stability of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xu, Ran, Xu, Yixi, Huo, Wei, Lv, Zhicong, Yuan, Jingsong, Ning, Shaokai, Wang, Qingsong, Hou, Mei, Gao, Ge, Ji, Jianguo, Chen, Junjie, Guo, Rong, Xu, Dongyi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205471/
https://ncbi.nlm.nih.gov/pubmed/30297404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806665115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados