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Nonproteinogenic deep mutational scanning of linear and cyclic peptides

High-resolution structure–activity analysis of polypeptides requires amino acid structures that are not present in the universal genetic code. Examination of peptide and protein interactions with this resolution has been limited by the need to individually synthesize and test peptides containing non...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Rogers, Joseph M., Passioura, Toby, Suga, Hiroaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205457/
https://ncbi.nlm.nih.gov/pubmed/30301798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809901115
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