Swi5–Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation

Eukaryotic Rad51 protein is essential for homologous-recombination repair of DNA double-strand breaks. Rad51 recombinases first assemble onto single-stranded DNA to form a nucleoprotein filament, required for function in homology pairing and strand exchange. This filament assembly is the first regul...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lu, Chih-Hao, Yeh, Hsin-Yi, Su, Guan-Chin, Ito, Kentaro, Kurokawa, Yumiko, Iwasaki, Hiroshi, Chi, Peter, Li, Hung-Wen
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205426/
https://ncbi.nlm.nih.gov/pubmed/30297419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812753115
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