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Swi5–Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation
Eukaryotic Rad51 protein is essential for homologous-recombination repair of DNA double-strand breaks. Rad51 recombinases first assemble onto single-stranded DNA to form a nucleoprotein filament, required for function in homology pairing and strand exchange. This filament assembly is the first regul...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205426/ https://ncbi.nlm.nih.gov/pubmed/30297419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812753115 |
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