E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs

Plasmacytoid dendritic cells (pDCs) play a key role in antiviral responses by producing type-1 IFNs. However, recent studies showed that pDCs induce immune suppression and promote tumor growth in human ovarian cancer and myeloma. The molecular mechanisms underlying pDC acquisition of these propertie...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bi, Enguang, Li, Rong, Bover, Laura C., Li, Haiyan, Su, Pan, Ma, Xingzhe, Huang, Chunjian, Wang, Qiang, Liu, Lintao, Yang, Maojie, Lin, Zhijuan, Qian, Jianfei, Fu, Weijun, Liu, Yong-Jun, Yi, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205396/
https://ncbi.nlm.nih.gov/pubmed/30277474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121421
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