Sympathetic β(1)-adrenergic signaling contributes to regulation of human bone metabolism

BACKGROUND. Evidence from rodent studies indicates that the sympathetic nervous system (SNS) regulates bone metabolism, principally via β(2)-adrenergic receptors (β(2)-ARs). Given the conflicting human data, we used multiple approaches to evaluate the role of the SNS in regulating human bone metabol...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Khosla, Sundeep, Drake, Matthew T., Volkman, Tammie L., Thicke, Brianne S., Achenbach, Sara J., Atkinson, Elizabeth J., Joyner, Michael J., Rosen, Clifford J., Monroe, David G., Farr, Joshua N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205387/
https://ncbi.nlm.nih.gov/pubmed/30153111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122151
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