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The post-2009 influenza pandemic era: time to revisit antibody immunodominance

The current inactivated influenza vaccines rely on the induction of neutralizing antibodies against the head domain of the viral hemagglutinin (HA). The HA head contains five immunodominant antigenic sites, all of which are subject to antigenic drift, thereby limiting vaccine efficacy. Bypassing the...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Yazar: Van Reeth, Kristien
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205375/
https://ncbi.nlm.nih.gov/pubmed/30295644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124151
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