Getting the Most: Enhancing Efficacy by Promoting Erythropoiesis and Thrombopoiesis after Gene Therapy in Mice with Hurler Syndrome

Novel strategies are needed to solve the conundrum of achieving clinical efficacy with high vector copy numbers (VCNs) in hematopoietic stem cells (HSCs) while attempting to minimize the potential risk of oncogenesis in lentiviral vector (LV)-mediated gene therapy clinical trials. We previously repo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Han, Jing-fen, El-Amouri, Salim S., Dai, Mei, Cao, Phuong, Pan, Dao
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205327/
https://ncbi.nlm.nih.gov/pubmed/30397627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.10.001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker