Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers

Chronic wounds are a complication of diabetes. Treatment for diabetic foot ulcers is complex with little clinical recourse, resulting in 108,000 lower-limb amputations annually in the United States alone. Matrix metalloproteinases (MMPs) play important roles in the pathology and in the repair of chr...

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Foilsithe in:Eur J Pharmacol
Main Authors: Nguyen, Trung T., Ding, Derong, Wolter, William R., Champion, Matthew M., Hesek, Dusan, Lee, Mijoon, Pérez, Rocio L., Schroeder, Valerie A., Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205151/
https://ncbi.nlm.nih.gov/pubmed/30012502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.07.014
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