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Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model

OBJECTIVE: HCV is characterised by its ability to establish chronic infection in hepatocytes and to replicate in the presence of an inflammation. We mimicked this situation in vivo in immune-competent mice by syngeneic transplantation of HCV replicon-containing mouse hepatoma cells. DESIGN: A total...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Levander, Sepideh, Holmström, Fredrik, Frelin, Lars, Ahlén, Gustaf, Rupp, Daniel, Long, Gang, Bartenschlager, Ralf, Sällberg, Matti
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204962/
https://ncbi.nlm.nih.gov/pubmed/28646094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313579
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