Loss of CXCR4/CXCL12 Signaling Causes Oculomotor Nerve Misrouting and Development of Motor Trigeminal to Oculomotor Synkinesis

PURPOSE: Proper control of eye movements is critical to vision, but relatively little is known about the molecular mechanisms that regulate development and axon guidance in the ocular motor system or cause the abnormal innervation patterns (oculomotor synkinesis) seen in developmental disorders and...

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Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Whitman, Mary C., Nguyen, Elaine H., Bell, Jessica L., Tenney, Alan P., Gelber, Alon, Engle, Elizabeth C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2018
Предметы:
Eye Movements, Strabismus, Amblyopia and Neuro-Ophthalmology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204880/
https://ncbi.nlm.nih.gov/pubmed/30372748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-25190
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