pH-sensitive PEGylation of RIPL peptide-conjugated nanostructured lipid carriers: design and in vitro evaluation

BACKGROUND: RIPL peptide (IPLVVPLRRRRRRRRC)-conjugated nanostructured lipid carriers (RIPL-NLCs) can facilitate selective drug delivery to hepsin (Hpn)-expressing cancer cells, but they exhibit low stability in the blood. Generally, biocompatible and nontoxic poly(ethylene glycol) surface modificati...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Kim, Chang Hyun, Sa, Cheol-Ki, Goh, Min Su, Lee, Eun Seok, Kang, Tae Hoon, Yoon, Ho Yub, Battogtokh, Gantumur, Ko, Young Tag, Choi, Young Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204877/
https://ncbi.nlm.nih.gov/pubmed/30425481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S184355
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