RIPL peptide-conjugated nanostructured lipid carriers for enhanced intracellular drug delivery to hepsin-expressing cancer cells

BACKGROUND: To facilitate selective and enhanced drug delivery to hepsin (Hpn)-expressing cancer cells, RIPL peptide (IPLVVPLRRRRRRRRC, 16-mer)-conjugated nanostructured lipid carriers (RIPL-NLCs) were developed. METHODS: NLCs were prepared using a solvent emulsification-evaporation method and the R...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Lee, Sang Gon, Kim, Chang Hyun, Sung, Si Woo, Lee, Eun Seok, Goh, Min Su, Yoon, Ho Yub, Kang, Myung Joo, Lee, Sangkil, Choi, Young Wook
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2018
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987859/
https://ncbi.nlm.nih.gov/pubmed/29910614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S166021
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