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New and emerging concepts in the use of denosumab for the treatment of osteoporosis
Denosumab is a fully human monoclonal antibody to receptor activator of nuclear factor kappa-B ligand (RANKL), a cytokine expressed by cells of the osteoblast lineage that is a key regulator of osteoclastic bone resorption. By binding and neutralizing RANKL, denosumab inhibits osteoclast differentia...
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| Gepubliceerd in: | Ther Adv Musculoskelet Dis |
|---|---|
| Hoofdauteur: | |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
SAGE Publications
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204627/ https://ncbi.nlm.nih.gov/pubmed/30386439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18805759 |
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