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New and emerging concepts in the use of denosumab for the treatment of osteoporosis

Denosumab is a fully human monoclonal antibody to receptor activator of nuclear factor kappa-B ligand (RANKL), a cytokine expressed by cells of the osteoblast lineage that is a key regulator of osteoclastic bone resorption. By binding and neutralizing RANKL, denosumab inhibits osteoclast differentia...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ther Adv Musculoskelet Dis
Päätekijä: Lewiecki, E. Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204627/
https://ncbi.nlm.nih.gov/pubmed/30386439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18805759
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