Therapeutic Targeting Cancer-Initiating Cell Markers by Exosome miRNA: Efficacy and Functional Consequences Exemplified for claudin7 and EpCAM()

AIM: Transfer of exosomes (Exo) miRNA was described interfering with tumor progression. We here explored for claudin7 (cld7) and EpCAM (EpC), cancer-initiating-cell markers in colorectal and pancreatic cancer, the efficacy of Exo loading with miRNA and miRNA transfer. METHODS: Exo were collected fro...

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Vydáno v:Transl Oncol
Hlavní autoři: Kyuno, Daisuke, Zhao, Kun, Bauer, Nathalie, Ryschich, Eduard, Zöller, Margot
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2018
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204435/
https://ncbi.nlm.nih.gov/pubmed/30393102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.08.021
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