Inhibition of Necroptosis Attenuates Lung Injury and Improves Survival in Neonatal Sepsis

BACKGROUND: Neonatal sepsis represents a unique therapeutic challenge owing to an immature immune system. Necroptosis is a form of programmed cell death that has been identified as an important mechanism of inflammation-induced cell death. Receptor-interacting protein kinase 1 (RIPK1) plays a key ro...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Bolognese, Alexandra C., Yang, Weng-Lang, Hansen, Laura W., Denning, Naomi-Liza, Nicastro, Jeffrey M., Coppa, Gene F., Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204110/
https://ncbi.nlm.nih.gov/pubmed/29709367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.02.017
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