A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

BACKGROUND: Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associated with clinical and in vitro resistance phenotypes; however, several studi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Malar J
Päätekijät: Breglio, Kimberly F., Amato, Roberto, Eastman, Richard, Lim, Pharath, Sa, Juliana M., Guha, Rajarshi, Ganesan, Sundar, Dorward, David W., Klumpp-Thomas, Carleen, McKnight, Crystal, Fairhurst, Rick M., Roberts, David, Thomas, Craig, Simon, Anna Katharina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204056/
https://ncbi.nlm.nih.gov/pubmed/30367653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2532-x
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