A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

BACKGROUND: Artemisinin-resistant Plasmodium falciparum has been reported throughout the Greater Mekong subregion and threatens to disrupt current malaria control efforts worldwide. Polymorphisms in kelch13 have been associated with clinical and in vitro resistance phenotypes; however, several studi...

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Publicat a:Malar J
Autors principals: Breglio, Kimberly F., Amato, Roberto, Eastman, Richard, Lim, Pharath, Sa, Juliana M., Guha, Rajarshi, Ganesan, Sundar, Dorward, David W., Klumpp-Thomas, Carleen, McKnight, Crystal, Fairhurst, Rick M., Roberts, David, Thomas, Craig, Simon, Anna Katharina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204056/
https://ncbi.nlm.nih.gov/pubmed/30367653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2532-x
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