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Does p53 Inhibition Suppress Myocardial Ischemia–Reperfusion Injury?

p53 is well known as a regulator of apoptosis and autophagy. In addition, a recent study showed that p53 is a modulator of the opening of the mitochondrial permeability transition pore (mPTP), a trigger event of necrosis, but the role of p53 in necrosis induced by myocardial ischemia–reperfusion (I/...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cardiovasc Pharmacol Ther
Hauptverfasser: Yano, Toshiyuki, Abe, Koki, Tanno, Masaya, Miki, Takayuki, Kuno, Atsushi, Miura, Tetsuji, Steenbergen, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203944/
https://ncbi.nlm.nih.gov/pubmed/29554809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248418763612
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