Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

Uric acid (UA) therapy may prevent early ischemic worsening after acute stroke in thrombolysis patients. The aim of this study was to examine the influence of UA on the thrombolytic efficacy of alteplase in human blood samples by measuring thrombolysis under flow conditions using a newly developed m...

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Publicado no:Sci Rep
Main Authors: Kikuchi, Kiyoshi, Setoyama, Kentaro, Tanaka, Eiichiro, Otsuka, Shotaro, Terashi, Takuto, Nakanishi, Kazuki, Takada, Seiya, Sakakima, Harutoshi, Ampawong, Sumate, Kawahara, Ko-ichi, Nagasato, Tomoka, Hosokawa, Kazuya, Harada, Yoichiro, Yamamoto, Mika, Kamikokuryo, Chinatsu, Kiyama, Ryoji, Morioka, Motohiro, Ito, Takashi, Maruyama, Ikuro, Tancharoen, Salunya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203847/
https://ncbi.nlm.nih.gov/pubmed/30367108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34220-1
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