Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis

The combination of alteplase, a recombinant tissue plasminogen activator, and edaravone, an antioxidant, reportedly enhances recanalization after acute ischemic stroke. We examined the influence of edaravone on the thrombolytic efficacy of alteplase by measuring thrombolysis using a newly developed...

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Publié dans:Oxid Med Cell Longev
Auteurs principaux: Kikuchi, Kiyoshi, Setoyama, Kentaro, Kawahara, Ko-ichi, Nagasato, Tomoka, Terashi, Takuto, Ueda, Koki, Nakanishi, Kazuki, Otsuka, Shotaro, Miura, Naoki, Sameshima, Hisayo, Hosokawa, Kazuya, Harada, Yoichiro, Shrestha, Binita, Yamamoto, Mika, Morimoto-Yamashita, Yoko, Kikuchi, Haruna, Kiyama, Ryoji, Kamikokuryo, Chinatsu, Tancharoen, Salunya, Sakakima, Harutoshi, Morioka, Motohiro, Tanaka, Eiichiro, Ito, Takashi, Maruyama, Ikuro
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702421/
https://ncbi.nlm.nih.gov/pubmed/29259732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6873281
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