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Mineralocorticoid Receptor Antagonism Reverses Diabetes-related Coronary Vasodilator Dysfunction: A Unique Vascular Transcriptomic Signature

Coronary microvascular dysfunction predicts and may be a proximate cause of cardiac dysfunction and mortality in diabetes; however, few effective treatments exist for these conditions. We recently demonstrated that mineralocorticoid receptor (MR) antagonism reversed cardiovascular dysfunction in ear...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Res
Hauptverfasser: Brown, Scott M., Meuth, Alex I., Davis, J. Wade, Scott Rector, R., Bender, Shawn B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203694/
https://ncbi.nlm.nih.gov/pubmed/29870805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.06.002
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