Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Uterine leiomyomas (ULs) are benign tumors that are a major burden to women’s health. A genome-wide association study on 15,453 UL cases and 392,628 controls was performed, followed by replication of the genomic risk in six cohorts. Effects of the risk alleles were evaluated in view of molecular and...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Välimäki, Niko, Kuisma, Heli, Pasanen, Annukka, Heikinheimo, Oskari, Sjöberg, Jari, Bützow, Ralf, Sarvilinna, Nanna, Heinonen, Hanna-Riikka, Tolvanen, Jaana, Bramante, Simona, Tanskanen, Tomas, Auvinen, Juha, Uimari, Outi, Alkodsi, Amjad, Lehtonen, Rainer, Kaasinen, Eevi, Palin, Kimmo, Aaltonen, Lauri A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Genetics and Genomics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203434/
https://ncbi.nlm.nih.gov/pubmed/30226466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37110
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