Modeling three-dimensional invasive solid tumor growth in heterogeneous microenvironment under chemotherapy

A systematic understanding of the evolution and growth dynamics of invasive solid tumors in response to different chemotherapy strategies is crucial for the development of individually optimized oncotherapy. Here, we develop a hybrid three-dimensional (3D) computational model that integrates pharmac...

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Veröffentlicht in:PLoS One
Hauptverfasser: Xie, Hang, Jiao, Yang, Fan, Qihui, Hai, Miaomiao, Yang, Jiaen, Hu, Zhijian, Yang, Yue, Shuai, Jianwei, Chen, Guo, Liu, Ruchuan, Liu, Liyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203364/
https://ncbi.nlm.nih.gov/pubmed/30365511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206292
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