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HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX
The centromere specific histone H3 variant CENP-A/CENH3 specifies where the kinetochore is formed in most eukaryotes. Despite tight regulation of CENP-A levels in normal cells, overexpression of CENP-A is a feature shared by various types of solid tumors and results in its mislocalization to non-cen...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6203356/ https://ncbi.nlm.nih.gov/pubmed/30365520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205948 |
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