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Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium

Adenosine triphosphate (ATP) modulates mechanosensitive vagal afferent nerves in the gastrointestinal tract. ATP is stored in secretory vesicles via the ATP transporter VNUT. Recently, the bisphosphate clodronate was reported to inhibit VNUT and was suggested to be a safe potent therapeutic option f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mihara, Hiroshi, Uchida, Kunitoshi, Koizumi, Schuichi, Moriyama, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203352/
https://ncbi.nlm.nih.gov/pubmed/30365528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206276
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