Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation

BACKGROUND: Transient receptor potential vanilloid 4 (TRPV4) is activated by stretch (mechanical), warm temperature, some epoxyeicosatrienoic acids, and lipopolysaccharide. TRPV4 is expressed throughout the gastrointestinal epithelia and its activation induces adenosine triphosphate (ATP) exocytosis...

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Udgivet i:Digestion
Main Authors: Mihara, Hiroshi, Boudaka, Ammar, Tominaga, Makoto, Sugiyama, Toshiro
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979422/
https://ncbi.nlm.nih.gov/pubmed/31770754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000504021
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