Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome

Placental ischemic disease and adverse pregnancy outcomes are frequently observed in patients with antiphospholipid syndrome (APS). Despite the administration of conventional antithrombotic treatment a significant number of women continue to experience adverse pregnancy outcomes, with uncertain prev...

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Veröffentlicht in:J Autoimmun
Hauptverfasser: Bertolaccini, Maria Laura, Contento, Gregorio, Lenner, Ross, Sanna, Giovanni, Blower, Philip J, Ma, Michelle, Sunassee, Kavitha, Girardi, Guillermina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203312/
https://ncbi.nlm.nih.gov/pubmed/27160365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.04.008
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