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Characterization of embryonic stem cell-differentiated fibroblasts as mesenchymal stem cells with robust expansion capacity and attenuated innate immunity

BACKGROUND: Mesenchymal stem cells (MSCs) isolated from adult tissues (Ad-MSCs) have shown great promise for use in regenerative medicine. However, their poor in vitro expansion capacity and tissue scarcity have been major limitations. In this study, we demonstrate that mouse embryonic stem cells (m...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: D’Angelo, William, Chen, Bohan, Gurung, Chandan, Guo, Yan-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203291/
https://ncbi.nlm.nih.gov/pubmed/30359317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1033-8
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