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The Molecular Basis for the Lack of Inflammatory Responses in Mouse Embryonic Stem Cells and Their Differentiated Cells

We have previously reported that mouse embryonic stem cells (mESCs) do not have a functional IFN-based antiviral mechanism. The current study extends our investigation to the inflammatory response in mESCs and mESC-differentiated cells. We demonstrate that LPS, TNFα, and viral infection, all of whic...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: D’Angelo, William, Gurung, Chandan, Acharya, Dhiraj, Chen, Bohan, Ortolano, Natalya, Gama, Vivian, Bai, Fengwei, Guo, Yan-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321812/
https://ncbi.nlm.nih.gov/pubmed/28130495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601068
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