The Molecular Basis for the Lack of Inflammatory Responses in Mouse Embryonic Stem Cells and Their Differentiated Cells

We have previously reported that mouse embryonic stem cells (mESCs) do not have a functional IFN-based antiviral mechanism. The current study extends our investigation to the inflammatory response in mESCs and mESC-differentiated cells. We demonstrate that LPS, TNFα, and viral infection, all of whic...

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Udgivet i:J Immunol
Main Authors: D’Angelo, William, Gurung, Chandan, Acharya, Dhiraj, Chen, Bohan, Ortolano, Natalya, Gama, Vivian, Bai, Fengwei, Guo, Yan-Lin
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321812/
https://ncbi.nlm.nih.gov/pubmed/28130495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601068
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