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NLRP3/Caspase-1 inflammasome activation is decreased in alveolar macrophages in patients with lung cancer

Lung cancer (LC) remains the leading cause of cancer-related mortality. The interaction of cancer cells with their microenvironment, results in tumor escape or elimination. Alveolar macrophages (AMs) play a significant role in lung immunoregulation, however their role in LC has been outshined by the...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Lasithiotaki, Ismini, Tsitoura, Eliza, Samara, Katerina D., Trachalaki, Athina, Charalambous, Irini, Tzanakis, Nikolaos, Antoniou, Katerina M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203254/
https://ncbi.nlm.nih.gov/pubmed/30365491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205242
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