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Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R

[Image: see text] Carbohydrate moieties are essential for the biological activity of anthracycline anticancer agents such as nogalamycin, which contains l-nogalose and l-nogalamine units. The former of these is attached through a canonical O-glycosidic linkage, but the latter is connected via an unu...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Siitonen, Vilja, Nji Wandi, Benjamin, Törmänen, Akke-Pekka, Metsä-Ketelä, Mikko
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2018
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203184/
https://ncbi.nlm.nih.gov/pubmed/30114358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00658
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