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Neovascular Age‐Related Macular Degeneration: A Visual Acuity Model of Natural Disease Progression and Ranibizumab Treatment Effect

Intravitreal ranibizumab is a first‐line therapy for neovascular age‐related macular degeneration (nAMD), but there is a need to optimize patient outcomes while minimizing treatment burden. Here, we developed an indirect response, nonlinear, mixed effects model of disease progression and drug effect...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:CPT Pharmacometrics Syst Pharmacol
Päätekijät: Mulyukov, Zufar, Weber, Sebastian, Pigeolet, Etienne, Clemens, Andreas, Lehr, Thorsten, Racine, Amy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202467/
https://ncbi.nlm.nih.gov/pubmed/30043524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12322
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