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Sublethal UV irradiation induces squamous differentiation via a p53-independent, DNA damage-mitosis checkpoint
The epidermis is a self-renewal epithelium continuously exposed to the genotoxic effects of ultraviolet (UV) light, the main cause of skin cancer. Therefore, it needs robust self-protective mechanisms facing genomic damage. p53 has been shown to mediate apoptosis in sunburn cells of the epidermis. H...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Cell Death Dis |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6202398/ https://ncbi.nlm.nih.gov/pubmed/30361544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1130-8 |
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