C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Core 1 β1,3-galactosyltransferase (C1GALT1) controls the crucial step of GalNAc-type O-glycosylation and is overexpressed in various human malignancies. However, its role in head and neck squamous cell carcinoma (HNSCC) remains unclear. Here we demonstrate that C1GALT1 expression is upregulated in H...

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Veröffentlicht in:Oncogene
Hauptverfasser: Lin, Mei-Chun, Chien, Pin-Hui, Wu, Hsin-Yi, Chen, Syue-Ting, Juan, Hsueh-Fen, Lou, Pei-Jen, Huang, Min-Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202324/
https://ncbi.nlm.nih.gov/pubmed/29930379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0375-0
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