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The intersection of lysosomal and endoplasmic reticulum calcium with autophagy defects in lysosomal diseases

The lysosomal storage disorders (LSDs) encompass a group of more than 50 inherited diseases characterized by the accumulation of lysosomal substrates. Two-thirds of patients experience significant neurological symptoms, but the mechanisms of neurodegeneration are not well understood. Interestingly,...

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Publicat a:Neurosci Lett
Autors principals: Liu, Elaine A., Lieberman, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202281/
https://ncbi.nlm.nih.gov/pubmed/29704574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.04.049
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