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An update on cell intrinsic negative regulators of the NLRP3 inflammasome

Inflammasomes are multimeric protein complexes that promote inflammation (through specific cleavage and production of bioactive IL-1β and IL-18) and pyroptotic cell death. The central role of inflammasomes in combating infection and maintaining homeostasis has been studied extensively. Although infl...

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Библиографические подробности
Опубликовано в: :J Leukoc Biol
Главные авторы: Poudel, Barun, Gurung, Prajwal
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202258/
https://ncbi.nlm.nih.gov/pubmed/29377242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MIR0917-350R
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