A Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

BACKGROUND: Platelets have distinct roles in the vascular system as they are the major mediator of thrombosis, critical for restoration of tissue integrity and players in vascular inflammatory conditions. In close spatiotemporal proximity, the complement system acts as the first line of defense agai...

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Publicat a:Circulation
Autors principals: Sauter, Reinhard J., Sauter, Manuela, Reis, Edimara S., Emschermann, Frederic N., Nording, Henry, Ebenhöch, Sonja, Kraft, Peter, Münzer, Patrick, Mauler, Maximilian, Rheinlaender, Johannes, Madlung, Johannes, Edlich, Frank, Schäffer, Tilman E., Meuth, Sven G., Dürschmied, Daniel, Geisler, Tobias, Borst, Oliver, Gawaz, Meinrad, Kleinschnitz, Christoph, Lambris, John D., Langer, Harald F.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202244/
https://ncbi.nlm.nih.gov/pubmed/29802205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.034600
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