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Membrane association of monotopic phosphoglycosyl transferase underpins function

Polyprenol phosphate phosphoglycosyl transferases (PGTs) catalyze the first membrane-committed step in assembly of essential glycoconjugates. Currently there is no structure-function information to describe how monotopic PGTs coordinate the reaction between membrane-embedded and soluble substrates....

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Detalles Bibliográficos
Publicado en:Nat Chem Biol
Main Authors: Ray, Leah C., Das, Debasis, Entova, Sonya, Lukose, Vinita, Lynch, Andrew J., Imperiali, Barbara, Allen, Karen N.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202225/
https://ncbi.nlm.nih.gov/pubmed/29769739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0054-z
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