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Analysis of a dual domain phosphoglycosyl transferase reveals a ping-pong mechanism with a covalent enzyme intermediate

Phosphoglycosyl transferases (PGTs) are integral membrane proteins with diverse architectures that catalyze the formation of polyprenol diphosphate-linked glycans via phosphosugar transfer from a nucleotide diphosphate-sugar to a polyprenol phosphate. There are two PGT superfamilies that differ sign...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Das, Debasis, Kuzmic, Petr, Imperiali, Barbara
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502628/
https://ncbi.nlm.nih.gov/pubmed/28630348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703397114
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