Llwytho...

Leishmania parasitophorous vacuole membranes display phosphoinositides that create conditions for continuous Akt activation and a target for miltefosine in Leishmania infections

Miltefosine is an important drug for the treatment of leishmaniasis; however, its mechanism of action is still poorly understood. In these studies, we tested the hypothesis that like in cancer cells, miltefosine’s efficacy in leishmaniasis is due to its inhibition of Akt activation in host cells. We...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Microbiol
Prif Awduron: Zhang, Naixin, Prasad, Samiksha, Despointes, Charles-Eugene Huyghues, Young, Jeffrey, Kima, Peter E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202129/
https://ncbi.nlm.nih.gov/pubmed/29993167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12889
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