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Combination of Ginsenoside Rg1 and Astragaloside IV reduces oxidative stress and inhibits TGF-β1/Smads signaling cascade on renal fibrosis in rats with diabetic nephropathy

INTRODUCTION: Anti-oxidative stress and inhibition of TGF-β1/Smads signaling cascade are essential therapeutic strategies for diabetic nephropathy (DN). In this study, we aimed to explore the effect of combination of Ginsenoside Rg1 and Astragaloside IV on oxidative stress and TGF-β1/Smads signaling...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Du, Na, Xu, Zhiping, Gao, Mingyue, Liu, Peng, Sun, Bo, Cao, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201993/
https://ncbi.nlm.nih.gov/pubmed/30425453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S171286
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