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Isolation and characterization of malaria PfHRP2 specific V(NAR) antibody fragments from immunized shark phage display library

BACKGROUND: Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (V(NAR)) from shark has a potential as altern...

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Publicat a:Malar J
Autors principals: Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Braet, Katleen, Cheng, Qin, McCarthy, James
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201582/
https://ncbi.nlm.nih.gov/pubmed/30355309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2531-y
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