Isolation and characterization of malaria PfHRP2 specific V(NAR) antibody fragments from immunized shark phage display library

BACKGROUND: Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (V(NAR)) from shark has a potential as altern...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Malar J
Prif Awduron: Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Braet, Katleen, Cheng, Qin, McCarthy, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201582/
https://ncbi.nlm.nih.gov/pubmed/30355309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2531-y
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