Isolation and characterization of malaria PfHRP2 specific V(NAR) antibody fragments from immunized shark phage display library

BACKGROUND: Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (V(NAR)) from shark has a potential as altern...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Braet, Katleen, Cheng, Qin, McCarthy, James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201582/
https://ncbi.nlm.nih.gov/pubmed/30355309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2531-y
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