Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology

The transepithelial potential difference (TEP) across the retinal pigment epithelial (RPE) is dependent on ionic pumps and tight junction “seals” between epithelial cells. RPE cells release neurotrophic growth factors such as pigment epithelial derived factor (PEDF), which is reduced in age‐related...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Cao, Lin, Liu, Jie, Pu, Jin, Milne, Gillian, Chen, Mei, Xu, Heping, Shipley, Alan, Forrester, John V, McCaig, Colin D, Lois, Noemi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201363/
https://ncbi.nlm.nih.gov/pubmed/30160348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13829
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