Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology

The transepithelial potential difference (TEP) across the retinal pigment epithelial (RPE) is dependent on ionic pumps and tight junction “seals” between epithelial cells. RPE cells release neurotrophic growth factors such as pigment epithelial derived factor (PEDF), which is reduced in age‐related...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Cao, Lin, Liu, Jie, Pu, Jin, Milne, Gillian, Chen, Mei, Xu, Heping, Shipley, Alan, Forrester, John V, McCaig, Colin D, Lois, Noemi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201363/
https://ncbi.nlm.nih.gov/pubmed/30160348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13829
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