Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases

Sirtuin3 (SIRT3) is associated with oxidative stress and lifespan. However, the possible mechanisms underlying its influence are unknown. We hypothesized that SIRT3 increases the antioxidant capacity of aged cells and improves the efficacy of human mesenchymal stem cell (hMSC) therapy for ischaemic...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Dong‐Yang, Zhang, Chun‐Feng, Fu, Bi‐Cheng, Sun, Lu, Wang, Xue‐Qing, Chen, Wei, Liu, Wei, Liu, Kai‐Yu, Du, Guo‐Qing, Ma, Chong‐Yi, Jiang, Shu‐Lin, Li, Ren‐Ke, Tian, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201360/
https://ncbi.nlm.nih.gov/pubmed/30091830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13821
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