Epithelial down‐regulation of the miR‐200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition

Intestinal mesenchymal cells deposit extracellular matrix in fibrotic Crohn's disease (CD). The contribution of epithelial to mesenchymal transition (EMT) to the mesenchymal cell pool in CD fibrosis remains obscure. The miR‐200 family regulates fibrosis‐related EMT in organs other than the gut....

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發表在:J Cell Mol Med
Main Authors: Mehta, Shameer J., Lewis, Amy, Nijhuis, Anke, Jeffery, Rosemary, Biancheri, Paolo, Di Sabatino, Antonio, Feakins, Roger, Silver, Andrew, Lindsay, James Oliver
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201355/
https://ncbi.nlm.nih.gov/pubmed/30188001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13836
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