Epithelial down‐regulation of the miR‐200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition

Intestinal mesenchymal cells deposit extracellular matrix in fibrotic Crohn's disease (CD). The contribution of epithelial to mesenchymal transition (EMT) to the mesenchymal cell pool in CD fibrosis remains obscure. The miR‐200 family regulates fibrosis‐related EMT in organs other than the gut....

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Mehta, Shameer J., Lewis, Amy, Nijhuis, Anke, Jeffery, Rosemary, Biancheri, Paolo, Di Sabatino, Antonio, Feakins, Roger, Silver, Andrew, Lindsay, James Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201355/
https://ncbi.nlm.nih.gov/pubmed/30188001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13836
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